English | 简体中文 | 繁體中文 | 한국어 | 日本語
Thursday, 23 March 2023, 13:30 JST

Source: Eisai
Eisai to Present New Lecanemab Data, Including Research Evaluating Safety Profile, Clinical Outcomes and Quality of Life Measures, as Well as Other Important Alzheimer's Disease Research, at the AD/PD 2023 Annual Meeting
Presentations Explore ARIA with the Use of Antiplatelets or Anticoagulants and Isolated ARIA-H in Patients from Eisai's Lecanemab Phase 3 Confirmatory Clarity AD Study in Early Alzheimer's Disease

TOKYO, Mar 23, 2023 - (JCN Newswire) - Eisai Co., Ltd. announced today the company will present the latest findings on lecanemab (generic name, U.S. brand name: LEQEMBI), Eisai's anti-amyloid beta (Aβ) protofibril* antibody for the treatment of Alzheimer's disease (AD), at the 2023 International Conference on Alzheimer's and Parkinson's Diseases and related neurological disorders (AD/PD) from March 28-April 1 in Gothenburg, Sweden and virtually. Eisai will present new findings from the company's large, global Phase III confirmatory study of lecanemab, Clarity AD, including research into the management and monitoring of amyloid-related imaging abnormalities (ARIA) and health-related quality of life (HRQoL) measures. Eisai will also host a symposium, titled "Patient Clinical Care Pathway in Alzheimer's disease: Dialogue Amongst Experts," which will address the evolving landscape in AD. The lecanemab data and additional research findings from Eisai's AD portfolio will be featured in 11 presentations, including seven oral and four poster presentations.

"Our latest research examines the real-world outcomes based on lecanemab's impact on clinical results and safety, including its effect on health-related quality of life. Through our ongoing research, we hope to help simplify the patient journey and improve the lives of those living with Alzheimer's disease," said Michael Irizarry, M.D., Deputy Chief Clinical Officer and Senior Vice President of Clinical Research at Eisai Inc. "In addition to lecanemab, Eisai is presenting on several other key issues that will shape the future of Alzheimer's disease and brain health, including the next generation of clinical care and diagnostic pathways, exploration of unique populations affected by the disease, and accelerating drug development. We look forward to sharing our latest findings, including new insights from Eisai's Clarity AD trial of lecanemab, with the scientific community at AD/PD 2023."

Key Eisai Lecanemab and AD Presentations

- Two presentations related to ARIA in the Clarity AD trial will be presented during an oral session on Thursday, March 30:
> An analysis evaluating the use of antiplatelet and anticoagulant drugs in patients who experienced ARIA.
> An analysis of isolated ARIA-H events in the Clarity AD trial.

- Research evaluating caregiver burden and HRQoL across multiple scales using Clarity AD data will be presented during an oral session on Thursday, March 30.

- Research studying the characterization of Aβ protofibrils and the unique binding properties and mechanisms of Aβ clearance of lecanemab on Friday, March 31.

- Designing The Next Generation Clinical Care and Diagnostic Pathway for Alzheimer's Disease: A presentation focused on a new pathway which interweaves clinical, biological and digital assessments to guide an individualized AD patient journey on Friday, March 31.

Eisai Symposium - Patient Clinical Care Pathway in AD: Dialogue Amongst Experts
Eisai is sponsoring a symposium featuring three prominent clinical experts in the field of AD, Dr. Alireza Atri, Dr. Sharon Cohen and Dr. Lutz Frolich, who will provide insights on the AD landscape, evolving diagnostic workflow, identifying appropriate patients, and addressing patient needs on Wednesday, March 29. The session aims to provide guidance on the clinical management of patients and drive effective communication between physicians and patients.

Eisai serves as the lead of lecanemab development and regulatory submissions globally with both Eisai and Biogen co-commercializing and co-promoting the product and Eisai having final decision-making authority.

* Protofibrils are large Aβ aggregated soluble species of 75-5000 Kd.1

Media Inquiries:
Public Relations Department,
Eisai Co., Ltd.

Eisai Europe, Ltd.
(Europe, Australia, New Zealand and Russia)
EMEA Communications Department
+44 (0) 786 601 1272

Eisai, Inc. (U.S.)
Libby Holman

For more information, visit www.eisai.com/news/2023/news202321.html.

Topic: Press release summary
Source: Eisai

Sectors: BioTech
From the Asia Corporate News Network

Copyright © 2024 ACN Newswire. All rights reserved. A division of Asia Corporate News Network.


Eisai Related News
Monday, 10 June 2024, 18:50 JST
FDA Accepts Eisai's Filing of LEQEMBI (lecanemab-irmb) Supplemental Biologics License Application for IV Maintenance Dosing for the Treatment of Early Alzheimer's Disease
2024年6月10日 13時00分 JST
Monday, 3 June 2024, 17:08 JST
Eisai Named to List of The Time 100 Most Influential Companies
Monday, 3 June 2024, 15:22 JST
Eisai Strengthens Venture Investment Business Aimed at Accelerating Drug Discovery Innovation and Establishment of Ecosystem Platform
2024年6月3日 14時00分 JST
エーザイ、創薬イノベーションおよびエコシステム プラットフォーム構築の加速に向けたベンチャー投資事業を強化
More news >>
Copyright © 2024 ACN Newswire - Asia Corporate News Network
Home | About us | Services | Partners | Events | Login | Contact us | Cookies Policy | Privacy Policy | Disclaimer | Terms of Use | RSS
US: +1 214 890 4418 | China: +86 181 2376 3721 | Hong Kong: +852 8192 4922 | Singapore: +65 6549 7068 | Tokyo: +81 3 6859 8575